GLP-3 RT from GLP3 Peptide Co. is a synthetic research peptide designed for activity at the GIP receptor (GIPR), GLP-1 receptor (GLP-1R) and glucagon receptor (GCGR), supplied as a white lyophilized powder in 10 mg, 15 mg and 30 mg vials. Every lot is independently tested, and its results are published as a lot record with the certificate PDF.
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Specifications and current testing status in one place.
"GLP-3 peptide" is the informal name researchers use for GLP-3 RT, a 39-residue synthetic peptide built to act on three receptors at once: GIPR, GLP-1R and the glucagon receptor. There is no natural hormone called GLP-3; the name describes the triple-receptor design. Its formula is C221H342N46O68 and its average molecular weight 4731.33 g/mol, and those two numbers are what every certificate checks the material against.
GLP3 Peptide Co. lists GLP-3 RT in 10 mg and 15 mg and 30 mg vials, currently $64.99 to $159.99 through Klow.bio. The newest lot, KB89232, reported 99.98% HPLC purity with LC-MS identity confirmed, and the full certificate for every lot is linked here.
"GLP-3" is an informal name for this three-receptor design. It does not refer to a naturally occurring hormone; there is no endogenous peptide called GLP-3. That is why GLP3 Labs identifies the material by its molecular data and lot results rather than by name alone.
Two α-aminoisobutyric acid (Aib) residues and one α-methyl-leucine constrain the peptide backbone. A C20 fatty diacid, attached to lysine 17 through a γ-glutamate and AEEA spacer, makes the molecule strongly hydrophobic, so it elutes late on reversed-phase HPLC. The C-terminus is amidated. The sequence contains no methionine, cysteine, tryptophan, histidine or asparagine.
Molecular characteristics, or the complete GLP-3 specifications.
Store sealed, dry and protected from light at the temperature stated on the vial label. Allow a cold vial to reach room temperature before opening. Lyophilized material absorbs moisture from the air, and absorbed moisture restarts the reactions that drying slows, so keep vials sealed until needed. Storage and stability guide.
| Product | GLP-3 RT |
|---|---|
| Type | Synthetic research peptide |
| Molecular formula | C221H342N46O68 |
| Molecular weight | 4731.33 g/mol (average) |
| Length | 39 residues |
| Sequence | Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-αMeLeu-Leu-Asp-Lys-[Lys(C20 diacid-γGlu-AEEA)]-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
| N-terminus | Free amine (Tyr1) |
| C-terminus | Amide (Ser39-NH2) |
| Non-standard residues | Aib (2, 20), α-methyl-leucine (13) |
| Side-chain modification | Lys17: C20 fatty diacid via γGlu-AEEA |
| Receptor design | GIP receptor (GIPR), GLP-1 receptor (GLP-1R) and glucagon receptor (GCGR) |
| Form | White lyophilized powder |
| Vial sizes | 10 mg, 15 mg, 30 mg |
| Purity specification | ≥95% (HPLC-UV) |
| Purity, current lots | 99.67%–99.98% |
| Storage | Store sealed, dry and protected from light at the temperature stated on the vial label. Allow a cold vial to reach room temperature before opening. |
| Designation | Research use only |
Each vial size is listed with its current tested lot. Price: from $64.99 to $159.99 depending on size, with bundle pricing (2 vials save 5%; 3 or more vials save 10%). Current prices are always on klow.bio.
| Vial size | Current lot | Purity (HPLC-UV) | Identity | Net content | Endotoxin | Certificate | Order |
|---|---|---|---|---|---|---|---|
| 10 mg | KB89232 | 99.98% | Confirmed | 13.15 mg | Pass | Lot KB89232 | Order 10 mg |
| 15 mg | KB48721 | 99.67% | Confirmed | 18.62 mg | Not tested | Lot KB48721 | Order 15 mg |
| 30 mg | KB3011 | 99.93% | Confirmed | 36.10 mg | Not tested | Lot KB3011 | Order 30 mg |
Ordering and shipping. GLP-3 RT is sold through klow.bio, operated by Klow Labs LLC. Orders ship the next business day. Same-day cutoff is 4:00 PM CT, with overnight and 2-day options at checkout. See shipping and returns.
All testing is performed by Freedom Diagnostics, an independent laboratory, on every lot.
Reversed-phase high-performance liquid chromatography separates the sample's components by hydrophobicity, and a UV detector records each as a peak. Purity is the main peak's area as a percentage of all detected peak area. GLP-3 RT elutes as a single sharp peak at about 14.4–14.9 minutes on current certificates.
Limits: does not identify the peak, and impurities that co-elute or absorb weakly in UV can be under-counted. More on HPLC
The separated sample enters a mass spectrometer via electrospray ionization, which gives the molecule one or more charges. The observed ions, near m/z 1578 (3+) and 1184 (4+), are matched against values calculated from GLP-3 RT's molecular weight of 4731.33.
Limits: confirms molecular weight, not amino-acid order. More on mass spectrometry
The Limulus amebocyte lysate assay, performed per USP <85>, detects lipopolysaccharide from Gram-negative bacteria. Where run, the method and result are printed on the lot record; lot KB89232: Pass (LAL assay per USP <85>, 2 replicates, sensitivity ≤0.05 EU/mL).
Limits: a pass means below the assay threshold for the sample tested. Reported per lot; the lot table shows which lots were tested.
A polymerase chain reaction assay amplifies genetic material from common microbial contaminants so it can be detected. Where run, the result is reported as detected or not detected.
Limits: detects DNA from targeted organisms only. It is not a sterility test and does not distinguish live from dead organisms.
The laboratory quantifies the main compound in the tested vial against a standard. It is reported in milligrams next to the labeled vial size.
Limits: measured on the vial tested; other vials from the same lot are expected to be similar but are not individually measured.
Observed ions on current certificates compared with values calculated from the molecular weight.
| Ion | Calculation | Expected m/z | Observed on COAs |
|---|---|---|---|
| [M+3H]3+ | (4731.33 + 3.02) ÷ 3 | 1578.1 | 1,578.0–1,578.3 |
| [M+4H]4+ | (4731.33 + 4.03) ÷ 4 | 1183.8 | 1,183.6 |
| [M+3H+K]4+ | (4731.33 + 3.02 + 39.10) ÷ 4 | 1193.4 | 1,193.0–1,193.1 |
| [M+3H+Na]4+ | (4731.33 + 3.02 + 22.99) ÷ 4 | 1189.3 | 1,189.0 (unassigned on COA) |
Expected values are calculated by GLP3 Peptide Co. from the average molecular weight (4731.33 g/mol; H+ 1.0073, Na+ 22.99, K+ 39.10). Observed values are as printed on each lot's mass confirmation panel.
HPLC-UV purity for each current lot.
GLP-3 RT is a synthetic research peptide designed for activity at the GIP receptor (GIPR), GLP-1 receptor (GLP-1R) and glucagon receptor (GCGR). GLP3 Peptide Co. supplies it as a white lyophilized powder in 10 mg, 15 mg, 30 mg vials, with an independent certificate of analysis for every lot.
GLP-3 research material is GLP-3 RT supplied for laboratory research, sold by lot, with each lot's identity, purity and net content documented by an independent laboratory in a published certificate of analysis.
"GLP-3" is an informal name for this three-receptor design. It does not refer to a naturally occurring hormone; there is no endogenous peptide called GLP-3. That is why GLP3 Labs identifies the material by its molecular data and lot results rather than by name alone.
The molecular formula is C221H342N46O68 and the average molecular weight is 4731.33 g/mol. The peptide has 39 residues.
Store sealed, dry and protected from light at the temperature stated on the vial label. Allow a cold vial to reach room temperature before opening.
There is no natural hormone named GLP-3. "GLP-3" is shorthand for GLP-3 RT, a synthetic 39-residue peptide designed for the GIP, GLP-1 and glucagon receptors.
None. "GLP-3 peptide" is the informal name; GLP-3 RT is the product name used on Klow.bio and on the certificates.
Current GLP-3 research material availability is provided through Klow.bio, the purchasing platform operated by Klow Labs: https://klow.bio/product/glp-3-rt/ Lot records, testing information and certificates of analysis are published on glp3peptide.bio so they can be reviewed before purchasing.
Yes. Purchasing information and current availability for GLP-3 research material are provided through Klow.bio: https://klow.bio/product/glp-3-rt/
Yes. Every lot is tested by Freedom Diagnostics, an independent laboratory, for HPLC-UV purity, LC-MS identity and net content. The stated release specification is ≥95% HPLC-UV purity with identity confirmed by LC-MS. The current lot, KB89232, reported 99.98% purity.
Enter the lot number from your vial label at glp3peptide.bio/verify/ to see that lot's results. To confirm with the laboratory directly: Scan the Freedom Diagnostics QR code printed on the certificate, then search for klow.bio under the Company tab to view the laboratory record.
The current price is from $64.99 to $159.99 depending on size, with bundle pricing (2 vials save 5%; 3 or more vials save 10%). Current pricing is always listed on Klow.bio.
Orders ship the next business day. Same-day cutoff is 4:00 PM CT, with overnight and 2-day options at checkout.
Sequence, composition, modifications and what they mean for identity testing.
Analytical methodsRetention time, peaks, area normalization and every lot's HPLC result.
Analytical methodsCharge states, expected vs. observed ions and mass error for every lot.
DocumentationEvery section of a GLP-3 COA, red flags, and what it does and doesn't prove.
Analytical methodsPurity vs. content vs. net content, impurity sources and comparing claims.
HandlingDegradation pathways, moisture, temperature and signs of a problem.
10 mg, 15 mg and 30 mg vials. Current lot KB89232 tested at 99.98% purity with identity confirmed by LC-MS. Current purchasing is available through Klow.bio.